One of the problems with the treatment of manic depression is the cycle of refusing to take medication...it is part of the illness...as the cycle moves from depression toward manic...and the euphoria sets in...the person feels better and therefore stops. Of course the crash is inevitable...back to depression and therefore the cycle starts again. Father, I pray that you would allow ths husband to understand his need to remain on his meds Supernaturally. I pray that he would stick with his regimen of meds and therapy to allow himself to think clearly. I pray that God intervenes and gives him wisdom and this wife patience and wisdom also in trying to repair the marriage. In Jesus name...Amen!